G-6-PDH is an enzyme which breaks down carbohydrates. It protects Red Blood Cells from haemolysis, oxidising drugs and infection. G-6-PDH deficiency is the most common enzyme disorder in the world affecting 400 million people. People with G-6-PDH deficiency should avoid red blood cell damaging triggers such as ingesting legumes and some drugs e.g. aspirin.
Symptoms which could prompt testing include genetic history, jaundice, dark urine, abdominal pain, back pain, lowered red blood cell count and elevated bilirubin levels. Those with severe G-6-PDH deficiency may also have gallstones, enlarged spleens, defective white blood cells and cataracts.
The Randox G6P-DH assay offers excellent analytical performance. PD2616 is a screening test and is suitable for manual use only.